They join dance music icon Robyn, who was previously confirmed as a headliner along with Run the Jewels.
The fest will also feature livestreams with talent from "Rick and Morty" and the world premiere of a new Run the Jewels music video.
The Grammy Award-nominated producer will appear at the first-ever "Adult Swim Con" virtual convention.
Adult Swim announced T-Pain, Flying Lotus and more to headline their annual music festival.
The popular rap duo have released a remix of "Stay Gold" through Adult Swim's singles program.